|
|
我將原標題的第一句話加了一個"問號"!
一直以來, 對於下標題的人(不論是記者 or 主編的決定)有點受不了...
將科學研究當作是連續劇的演進來做處理...
研究就是研究
要有怎麼樣的驚人結果, 不是說說就可以的啊!
當然
我也是希望一些研究, 真的可以有朝一日用於幫助人類的身上
後面的那一小段
是該篇文章的 Abstract 與暫時的網址
==============================================================
愛滋病不再是絕症 科學家找到治療關鍵
http://tw.news.yahoo.com/article/url/d/a/090623/1/1lr6e.html
加拿大和美國研究人員指出，他們發現了可能會徹底治愈愛滋病的新方法，愛滋病將可能不再是絕症。
美、加科學家在最新英國「自然醫學」期刊上發表論文指出，他們找到了愛滋病病毒在人體內的藏身之地，這個潛伏池，就是「記憶T細胞」，他們發現細胞活著病毒也就活著；細胞死亡病毒也就死亡；包括病毒增殖也完全依賴於細胞的分裂。也因此，摧毀「記憶T細胞」，也就可以摧毀躲藏起來的愛滋病病毒。
研究人員也據此提出了結合化學療法和「抗逆轉錄病毒療法」來治療愛滋病的新方法，其中，「抗逆轉錄病毒療法」可以殺滅人體內大部分的愛滋病毒。而化學療法則是專門針對躲藏在「記憶T細胞」中的愛滋病毒，使愛滋病毒在人體中再無藏身之地.....................
===========================================================
HIV reservoir size and persistence are driven by T cell survival and homeostatic proliferation
http://www.nature.com/nm/journal/vaop/ncurrent/pdf/nm.1972.pdf
HIV persists in a reservoir of latently infected CD4+ T cells in individuals treated with highly active antiretroviral therapy (HAART). Here we identify central memory (TCM) and transitional memory (TTM) CD4+ T cells as the major cellular reservoirs for HIV and find that viral persistence is ensured by two different mechanisms. HIV primarily persists in TCM cells in subjects showing reconstitution of the CD4+ compartment upon HAART. This reservoir is maintained through T cell survival and low-level antigen-driven proliferation and is slowly depleted with time. In contrast, proviral DNA is preferentially detected in TTM cells from aviremic individuals with low CD4+ counts and higher amounts of interleukin-7–mediated homeostatic proliferation, a mechanism that ensures the persistence of these cells. Our results suggest that viral eradication might be achieved through the combined use of strategic interventions targeting viral replication and, as in cancer, drugs that interfere with the self renewal and persistence of proliferating memory T cells.
=================================================================
[ 本文最後由 wang.hurh 於 2009-6-23 17:53 編輯 ] |
評分
-
查看全部評分
|
發表於 2009-6-23 09:08:04
樓主